Intratumoral nuclear morphologic heterogeneity in prostate cancer
نویسندگان
چکیده
منابع مشابه
Intratumoral metabolic heterogeneity of cervical cancer.
PURPOSE Previous research has shown that the intertumoral maximum standardized uptake value (SUVMax) of F-18 fluorodeoxyglucose (FDG)-positron emission tomography (PET) for cervical cancer predicts disease outcome. The purpose of this study was to evaluate the pretreatment intratumoral metabolic heterogeneity of FDG. EXPERIMENTAL DESIGN This is a prospective cohort study of 72 patients with I...
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PURPOSE The aim of this study was to investigate the effect of VEGF-targeted therapy (sunitinib) on molecular intratumoral heterogeneity (ITH) in metastatic clear cell renal cancer (mccRCC). EXPERIMENTAL DESIGN Multiple tumor samples (n = 187 samples) were taken from the primary renal tumors of patients with mccRCC who were sunitinib treated (n = 23, SuMR clinical trial) or untreated (n = 23,...
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INTRODUCTION An increasing number of studies have investigated microRNAs (miRNAs) as potential markers of diagnosis, treatment and prognosis. So far, agreement between studies has been minimal, which may in part be explained by intratumoral heterogeneity of miRNA expression. The aim of the present study was to assess the heterogeneity of a panel of selected miRNAs in rectal cancer, using two di...
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Evolution of intratumoral genetic heterogeneity during colorectal tumor progression has not been investigated so far. Multiple sample areas in colorectal adenocarcinoma at early and advanced stages and in metastases were studied for the well-known genetic alterations: K-ras and p53 point mutations and loss of heterozygosity (LOH) on chromosomes 5q and 18q. In primary colorectal cancers (CRCs), ...
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Recently, Mikheil Gogiashvili and colleagues from TU-Dortmund have published a study about the metabolomics heterogeneity of breast cancer (Gogiashvili et al., 2017). The background of this study is the practically relevant question, whether measurement of a single biopsy is sufficient when analyzing tumors from a cohort of patients. In recent years metabolic profiling by high-resolution magic ...
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ژورنال
عنوان ژورنال: Urology
سال: 1997
ISSN: 0090-4295
DOI: 10.1016/s0090-4295(96)00557-2